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The First of the Great Few


Jeffrey C Hall, Michael Rosbash and Michael W Young, have been awarded the 2017 Nobel prize in Physiology or Medicine for ‘their discoveries of molecular mechanisms controlling the circadian rhythm’. The first of the Nobel Prizes to be given out, these three share the The Nobel Prize in Physiology or Medicine 2017.

The study concludes "The discovery of self-sustained transcription/ translation feedback loops as the central component of the molecular mechanism by which clock genes control circadian oscillations in cells and tissues has led to a new paradigm in our understanding of how organisms anticipate and adapt to the regular daily environmental cues such as light. Since the seminal discoveries by the three laureates, elucidating a fundamental physiological mechanism, circadian biology has developed into a vast and highly dynamic research field, with important implications for our health and wellbeing."

 

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